Cedars-Sinai Medical Center - AI may detect earliest signs of pancreatic cancer [Medical Xpress, April 2022]

Title:

AI may detect earliest signs of pancreatic cancer

 

By:

Cedars-Sinai Medical Center, United States of America

 

Published:

Medical Xpress, 26 April 2022

https://medicalxpress.com/news/2022-04-ai-earliest-pancreatic-cancer.html

 

From the article:

An artificial intelligence (AI) tool developed by Cedars-Sinai investigators accurately predicted who would develop pancreatic cancer based on what their CT scan images looked like years prior to being diagnosed with the disease. The findings, which may help prevent death through early detection of one of the most challenging cancers to treat, are published in the journal Cancer Biomarkers. 

 

DNA-based cancer vaccine triggers immune attack on tumors [Futurity, April 2021]

Title:

DNA-based cancer vaccine triggers immune attack on tumors 

 

Author:

Jim Goodwin-Wustl

 

Published:

Futurity, 23 April 2021

https://www.futurity.org/dna-cancer-vaccine-2553722/

 

From the article:

Researchers have shown that personalized cancer vaccines made using DNA can program the immune system to attack malignant tumors, including breast and pancreatic cancers. The researchers conducted the study in mice with breast cancer and one patient with late-stage pancreatic cancer.

 

Also see

 

Li, L., Zhang, X., Wang, X. et al. Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Genome Med 13, 56 (2021). 

https://doi.org/10.1186/s13073-021-00872-4

University of Pennsylvania - Scientists Unveil a Promising New Strategy For Combating Pancreatic Cancer

Title:

Scientists Unveil a Promising New Strategy For Combating Pancreatic Cancer: Common mutation in pancreatic cancer creates a sensitivity to some PARP1 inhibitor drugs

 

Published:

Penn Medicine News (Press Release), University of Pennsylvania, 14 December 2020

https://www.pennmedicine.org/news/news-releases/2020/december/scientists-unveil-a-promising-new-strategy-for-combating-pancreatic-cancer

 

From the article:

A DNA mutation that occurs frequently in the development of many pancreatic tumors appears to make these cancers vulnerable to an existing type of drug known as PARP inhibitors, according to a new study from scientists in the Perelman School of Medicine at the University of Pennsylvania.