Title:
DNA-based cancer vaccine triggers immune attack on tumors
Author:
Jim Goodwin-Wustl
Published:
Futurity, 23 April 2021
From the article:
Researchers have shown that personalized cancer vaccines made using DNA can program the immune system to attack malignant tumors, including breast and pancreatic cancers. The researchers conducted the study in mice with breast cancer and one patient with late-stage pancreatic cancer.
Also see
Li, L., Zhang, X., Wang, X. et al. Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Genome Med 13, 56 (2021).