Keck School of Medicine, University of Southern California, USA - Generosity Could Be an Early Sign of Alzheimer’s [SciTechDaily, July 2022]

Title:

Generosity Could Be an Early Sign of Alzheimer’s

 

By:

Keck School of Medicine at University of Southern California (USC), USA 

Published:

SciTechDaily, 19 July 2022

https://scitechdaily.com/generosity-could-be-an-early-sign-of-alzheimers/

 

From the article:

Researchers are attempting to identify those who are most vulnerable to financial exploitation in order to help protect older adults. Recent research from the Keck School of Medicine at USC suggests a connection between financial generosity and the early stages of Alzheimer’s disease. These results were recently published in the Journal of Alzheimer’s Disease.

 

Propofol Anesthesia Alters Cortical Traveling Waves [Scholarly Article - Journal of Cognitive Neuroscience, April 2022]

Title:

Propofol Anesthesia Alters Cortical Traveling Waves

 

Authors:

Sayak Bhattacharya, Jacob A. Donoghue, Meredith Mahnke, Scott L. Brincat, Emery N. Brown & Earl K. Miller 

* They are all from the Massachusetts Institute of Technology, Cambridge

 

Published:

Journal of Cognitive Neuroscience,  15 April 2022

https://direct.mit.edu/jocn/article-abstract/doi/10.1162/jocn_a_01856/110680/Propofol-Anesthesia-Alters-Cortical-Traveling

Abstract:

Oscillatory dynamics in cortex seem to organize into traveling waves that serve a variety of functions. Recent studies show that propofol, a widely used anesthetic, dramatically alters cortical oscillations by increasing slow-delta oscillatory power and coherence. It is not known how this affects traveling waves. We compared traveling waves across the cortex of non-human primates before, during, and after propofol-induced loss of consciousness (LOC). After LOC, traveling waves in the slow-delta (∼1 Hz) range increased, grew more organized, and traveled in different directions relative to the awake state. Higher frequency (8–30 Hz) traveling waves, by contrast, decreased, lost structure, and switched to directions where the slow-delta waves were less frequent. The results suggest that LOC may be due, in part, to increases in the strength and direction of slow-delta traveling waves that, in turn, alter and disrupt traveling waves in the higher frequencies associated with cognition.