Alzheimer's can be 'stalled or reversed' using oxygen [The National News, September 2021]

Title:

Alzheimer's can be 'stalled or reversed' using oxygen

Author:

Tim Kiek

Published:

The National News, 10 September 2021 [updated 15 September 2021]

https://www.thenationalnews.com/mena/2021/09/10/alzheimers-can-be-stalled-or-reversed-using-oxygen/

 

From the article:

Alzheimer's disease can be effectively treated by giving oxygen to patients in pressurised chambers, a study from Tel Aviv University suggests.

 

Hong Kong University of Science and Technology (HKUST) - Genome-editing strategy developed for potential Alzheimer’s therapy [Mirage, August 2021]

Title:

Genome-editing strategy developed for potential Alzheimer’s therapy 

 

Published:

Mirage, 18 August 2021

https://www.miragenews.com/genome-editing-strategy-developed-for-potential-615191/

 

From the article:

An international research team led by scientists from the Hong Kong University of Science and Technology (HKUST) has developed a novel strategy using brain-wide genome-editing technology that can reduce Alzheimer’s disease (AD) pathologies in genetically modified AD mouse models. This advanced technology offers immense potential to be translated as a novel long-acting therapeutic treatment for AD patients.

 

Also see

 

Yangyang Duan, Tao Ye, Zhe Qu, Yuewen Chen, Abigail Miranda, Xiaopu Zhou, Ka-Chun Lok, Yu Chen, Amy K. Y. Fu, Viviana Gradinaru, Nancy Y. Ip. Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice. Nature Biomedical Engineering, 2021

DOI: 10.1038/s41551-021-00759-0

 

Massachusetts General Hospital & Harvard Medical School - Artificial intelligence reveals current drugs that may help combat Alzheimer's disease

Title:

Artificial intelligence reveals current drugs that may help combat Alzheimer's disease

 

By:

Massachusetts General Hospital 

Published:

Medical Xpress, 4 March 2021

https://medicalxpress.com/news/2021-03-artificial-intelligence-reveals-current-drugs.html

 

From the article:

New treatments for Alzheimer's disease are desperately needed, but numerous clinical trials of investigational drugs have failed to generate promising options. Now a team at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) has developed an artificial intelligence-based method to screen currently available medications as possible treatments for Alzheimer's disease. The method could represent a rapid and inexpensive way to repurpose existing therapies into new treatments for this progressive, debilitating neurodegenerative condition. Importantly, it could also help reveal new, unexplored targets for therapy by pointing to mechanisms of drug action.

 

University of Otago, New Zealand - Scientists Invented a Wearable Device That Can Prevent Alzheimer's Disease [The Science Times, 23 December 2020]

Title:

Scientists Invented a Wearable Device That Can Prevent Alzheimer's Disease

 

Author:

Erika P.

 

Published:

The Science Times, 23 December 2020

https://www.sciencetimes.com/articles/28785/20201223/scientists-invented-wearable-prevent-alzheimers-disease.htm

From the article:

A team of scientists from the University of Otago unveiled a new wearable device strapped across the head and produces electrical pulses to arouse the olfactory nerves. That area is usually known to be dysfunctional during the early stages of Alzheimer's disease.

This Google Glass-like device is fitted with six electrodes placed near the temporal lobe, a part of the brain that controls the organization of sensory input. It is said that this new device will prevent Alzheimer's disease.

Indiana University Bloomington - Can 'the social brain' protect against Alzheimer's? NIH awards IU team $3.5 million to find out

Title:

Can 'the social brain' protect against Alzheimer's? NIH awards IU team $3.5 million to find out

 

Published:

Indiana University, 19 November 2020

https://news.iu.edu/stories/2020/11/iub/releases/19-nih-funding-alzheimers-disease-social-connectedness.html?_ga=2.47815527.1315323179.1608711046-1213314253.1608711046

 

From the article:

An interdisciplinary team led by Indiana University social neuroscientist Anne Krendl was awarded $3.5 million by the National Institutes of Health to navigate a phenomenon with major promise for the treatment of Alzheimer's disease: that the social connectedness of older adults predicts their vulnerability to Alzheimer's and general cognitive decline.

Research led by University of Cambridge - Star-Shaped Protein Once Thought "Undruggable" Is Target of Alzheimer's Study

Title:

Star-Shaped Protein Once Thought "Undruggable" Is Target of Alzheimer's Study

 

Source:

Original story from the University of Cambridge

 

Published:

Technology Networks, 5 November 2020

https://www.technologynetworks.com/neuroscience/news/star-shaped-protein-once-thought-undruggable-is-new-target-in-alzheimers-disease-342449

 

From the article:

A new study suggests that it is possible to design drugs that can target a type of shape-shifting protein involved in Alzheimer's disease, which was previously thought to be undruggable.  

 

A team of researchers, led by the University of Cambridge, have identified a new mechanism of targeting amyloid-beta, a protein fragment that clumps together and kills healthy brain cells in people with Alzheimer's disease.

Florida State University - Researchers uncover new insights into Alzheimer's disease

Title:
Researchers uncover new insights into Alzheimer's disease

Author:
Amy Robinson

Published:
Medical Xpress, 18 June 2020
https://medicalxpress.com/news/2020-06-uncover-insights-alzheimer-disease.html

From the article:
A new study by Florida State University researchers may help answer some of the most perplexing questions surrounding Alzheimer's disease, an incurable and progressive illness affecting millions of families around the globe.

Tufts University - 3-D brain-like tissue model links Alzheimer's disease with herpes

Title:
3-D brain-like tissue model links Alzheimer's disease with herpes

By:
Tufts University

Published:
Medical Xpress, 6 May 2020

From the article:
"Engineers and scientists led by Tufts University used a three-dimensional (3-D) human tissue culture model mimicking the components and conditions in the brain to demonstrate a possible causal relationship between sporadic Alzheimer's disease and herpes simplex virus I infection (HSV-1). Reported today in Science Advances, the model will allow for further studies into the causes and possible treatments of this devastating neurodegenerative condition."

To read this article:
https://medicalxpress.com/news/2020-05-d-brain-like-tissue-links-alzheimer.html

Phys.org, 30 April 2020 - Nanodevices for the brain could thwart formation of Alzheimer's plaques

Title:
Nanodevices for the brain could thwart formation of Alzheimer's plaques

Author:
Savannah Mitchem

Published:
Phys.org, 30 April 2020

From the article:
"Alzheimer's disease is the sixth leading cause of death in the United States, affecting one in 10 people over the age of 65. Scientists are engineering nanodevices to disrupt processes in the brain that lead to the disease."

To read this article:
https://phys.org/news/2020-04-nanodevices-brain-thwart-formation-alzheimer.html

University of Geneva & University Hospitals of Geneva, Switzerland - Personality traits found to be protective in Alzheimer's disease

Title:
Personality traits found to be protective in Alzheimer's disease

By:
University of Geneva

Published:
Medical Xpress, 12 March 2020

From the article:
"Scientists from the University of Geneva (UNIGE) and the University Hospitals of Geneva (HUG), Switzerland, demonstrated, through brain imaging and psycho-cognitive evaluations conducted over several years on a community-based cohort of elderly people, that certain personality traits protect brain structures against neuro-degeneration."

To read this article:
https://medicalxpress.com/news/2020-03-brain-dont-kind.html

University of Alabama at Birmingham: Pathogenic Alzheimer's disease cascade is activated by faulty norepinephrine signaling

Title:
Pathogenic Alzheimer's disease cascade is activated by faulty norepinephrine signaling

Author:
University of Alabama at Birmingham

Published:
Medical Xpress, 15 Jannuary 2020

From the article:
"In preclinical experiments, University of Alabama at Birmingham researchers have revealed a key missing piece of the Alzheimer's disease puzzle. That allowed proof-of-concept experiments - using an existing drug - that dramatically reduced Alzheimer's pathology and symptoms in two mouse models, potentially offering an immediate treatment for this devastating disease."

To read this article:
https://medicalxpress.com/news/2020-01-pathogenic-alzheimer-disease-cascade-faulty.html