Title:
Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility
Published:
Sveriges lantbruksuniversitet / Swedish University of Agricultural Sciences (SLU), 8 July 2021
From the article:
Topical ophthalmic atropine sulfate is an important part of the treatment protocol in equine uveitis. Frequent administration of topical atropine may cause decreased intestinal motility and colic in horses due to systemic exposure. Atropine pharmacokinetics are unknown in horses and this knowledge gap could impede the use of atropine because of the presumed risk of unwanted effects. Additional information could therefore increase safety in atropine treatment.
Also see
Ström, L. Dalin, F. Domberg, M. Stenlund, C. Bondesson, U. Hedeland, M. Toutain, P-L. Ekstrand, C. 2021. Topical ophthalmic atropine in horses, pharmacokinetics and effect on intestinal motility. BMC Veterinary Research. (2021) 17:149