Title:
Genetically engineered Nanoparticle Delivers Dexamethasone Directly to Inflamed Lungs
By:
University of California San Diego
Published:
Newswise, 15 June 2021
From the article:
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they’re needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue. Inflammation was completely treated in mice given the nanoparticles, at a drug concentration where standard delivery methods did not have any efficacy.
The researchers reported their findings in Science Advances on June 16.