University of Buffalo, New York - New technique can print life-like organ models in minutes [News Medical Life Sciences, May 2021]

Title:

New technique can print life-like organ models in minutes

 

Reviewed by:

Emily Henderson, B.Sc.

 

Published:

News Medical Life Sciences, 6 May 2021

https://www.news-medical.net/news/20210506/New-technique-can-print-life-like-organ-models-in-minutes.aspx

 

From the article:

NIBIB-funded engineers at the University of Buffalo have fine-tuned the use of stereolithography for 3D printing of organ models that contain live cells. The new technique is capable of printing the models 10-50 times faster than the industry standard-;in minutes instead of hours-; a major step in the quest to create 3D-printed replacement organs.

Also see

Anandakrishnan, N., et al. (2021) Fast Stereolithography Printing of Large‐Scale Biocompatible Hydrogel Models. Advanced Healthcare Materials. doi.org/10.1002/adhm.202002103

University at Buffalo - Researchers Devise Rapid 3D Printing Method for Human Organs

Title:

Researchers Devise Rapid 3D Printing Method for Human Organs 

 

Author:

Elizabeth Montalbano

Published:

DesignNews, 2 March 2021

https://www.designnews.com/3dp/researchers-devise-rapid-3d-printing-method-human-organs

From the article:

The Holy Grail of 3D bioprinting is to one day be able to fabricate full-sized human organs and tissues to replace the real thing in cases of transplant surgeries and other biomedical applications. Researchers at the University at Buffalo have made a significant step not only to achieve this endeavor but to do it quickly. A team of researchers there has developed 3D-printing technology that has demonstrated rapid printing of life-sized organs and limbs such as a human hand in less than 20 minutes.

High-Speed 3D Printing Method Takes Us One Step Closer to Printing Organs - The new method uses stereolithography and jelly-like materials known as hydrogels to speed up the process [Interesting Engineering, 2021]

Title:

High-Speed 3D Printing Method Takes Us One Step Closer to Printing Organs

 

Author:

Loukia Papadopoulos

 

Published:

Interesting Engineering, 7 March 2021

https://interestingengineering.com/high-speed-3d-printing-takes-us-closer-to-printing-organs

 

From the article:

3D printing technologies have evolved at an unbelievable pace resulting in everything from 3D printed meat, to 3D printed houses to even 3D printed guns. Many 3D printers have boasted that they may be the future of printed organs but we haven't gotten there just yet. Now, a new study out of the University of Buffalo may just be the key to 3D printed organs.

 

Also see:

 

Title:

Fast Stereolithography Printing of Large‐Scale Biocompatible Hydrogel Models 

 

Authors:

Nanditha Anandakrishnan,  Hang Ye,  Zipeng Guo,  [et al.]

Published:

Advanced Healthcare Materials, 15 February 2021

https://onlinelibrary.wiley.com/doi/10.1002/adhm.202002103

Abstract:

Large size cell‐laden hydrogel models hold great promise for tissue repair and organ transplantation, but their fabrication using 3D bioprinting is limited by the slow printing speed that can affect the part quality and the biological activity of the encapsulated cells. Here a fast hydrogel stereolithography printing (FLOAT) method is presented that allows the creation of a centimeter‐sized, multiscale solid hydrogel model within minutes. Through precisely controlling the photopolymerization condition, low suction force‐driven, high‐velocity flow of the hydrogel prepolymer is established that supports the continuous replenishment of the prepolymer solution below the curing part and the nonstop part growth. The rapid printing of centimeter‐sized hydrogel models using FLOAT is shown to significantly reduce the part deformation and cellular injury caused by the prolonged exposure to the environmental stresses in conventional 3D printing methods. Embedded vessel networks fabricated through multiscale printing allows media perfusion needed to maintain the high cellular viability and metabolic functions in the deep core of the large‐sized models. The endothelialization of this vessel network allows the establishment of barrier functions. Together, these studies demonstrate a rapid 3D hydrogel printing method and represent a first step toward the fabrication of large‐sized engineered tissue models.